人类细胞揭开鱿鱼伪装的秘密

鱿鱼和章鱼是伪装大师,能融入他们的环境以逃避捕食者或攻击猎物。这些头足纲动物的可逆透明度有些机制仍不清楚,主要是因为研究人员无法在实验室中培养头足类动物的皮肤细胞。然而,如今,研究人员报告说,他们已在能够培养的哺乳类细胞中复制了某些鱿鱼皮肤细胞的可调透明度。这项工作不仅能够阐明基本的鱿鱼生物学,还能够提高多种细胞类型的成像方式。

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加利福尼亚大学尔湾分校的团队集中精力研究称为浆细胞的头足类细胞,引入源自鱿鱼的反光蛋白基因到人类细胞中。通过向细胞培养基添加盐,他们观察到反光蛋白形成的纳米结构改变了细胞的透明度。这项研究不仅有助于理解鱿鱼生物学,还为基于固有光学特性的先进细胞成像策略开启了可能性。

多年来,阿隆·戈罗德茨基博士和他的研究团队一直致力于鱿鱼启发的材料研究,过去,他们开发了“隐形贴纸”,其中包括由细菌生产的反光蛋白,贴在带状胶带上。戈罗德茨基说:“然后,我们有了这个疯狂的想法,想看看能否在人类细胞培养中捕捉到鱿鱼皮肤组织改变透明度的某些方面。”

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研究人员将注意力集中在称为浆细胞的头足类细胞上,这些细胞具有由反射蛋白组成的颗粒状纳米结构,能够散射光线。通常,反光素聚集在一起形成纳米粒子,因此光线不被吸收或直接传递;相反,光线会散射或弹回,使浆细胞显得明亮。

戈罗德茨基说:“我们希望能够使哺乳动物的细胞稳定地形成反光素纳米结构,而不是临时性的,从而更好地控制光的散射。”因为如果细胞让光透过而且几乎不散射,它们会变得更

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The Market Research Report On Rock Wool Roof Insulation And Its Prominent Market Players with a 5.2% CAGR Forecasted from 2023 to 2030

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作者 刘军

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